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| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Hematology | 20-25% | - Red blood cell physiology and disorders - Hemostasis and coagulation testing - Routine and automated hematology procedures - White blood cell morphology and diseases |
| Topic 2: Clinical Chemistry | 20-25% | - Electrolytes, acid-base balance, and blood gases - Toxicology and liver/kidney function tests - Endocrinology and therapeutic drug monitoring - Carbohydrates, lipids, proteins, and enzymes |
| Topic 3: Immunology and Serology | 5-10% | - Infectious disease serology - Immunologic testing methodologies - Immune system principles and components - Autoimmune and immunodeficiency disorders |
| Topic 4: Blood Banking (Immunohematology) | 15-20% | - Transfusion reactions and adverse events - Compatibility testing - Antibody detection and identification - Blood group systems and antigens - Blood components and storage |
| Topic 5: Microbiology | 15-20% | - Mycology, parasitology, and virology - Identification of pathogenic microorganisms - Bacteriology and antimicrobial susceptibility - Specimen collection and culture techniques |
| Topic 6: Urinalysis and Other Body Fluids | 5-10% | - Urine formation and composition - Physical, chemical, and microscopic analysis - Cerebrospinal, serous, and synovial fluids - Semen and amniotic fluid testing |
| Topic 7: Laboratory Operations | 5-10% | - Laboratory mathematics and instrumentation - Pre-analytical, analytical, and post-analytical processes - Laboratory safety and regulatory compliance - Quality control and quality assurance |
1. The correct answer which best fits the characteristics in this question is Mycobacterium tuberculosis.
What is the MOST likely identity of an acid-fast bacilli that showed buff colored, dry, heaped colonies; niacin, nitrate, and urease positive; and took 23 days at 35ºC to grow?
A) Mycobacterium kansasii
B) Mycobacterium avium
C) Mycobacterium leprae
D) Mycobacterium bovis
E) Mycobacterium tuberculosis
2. High-sensitivity C-reactive protein (hs-CRP) is used as an aid in the diagnosis and treatment of cardiovascular disease (CVD). At low levels, it can detect those at risk for cardiac heart disease. At high levels in those with no history of heart disease, it indicates a high risk for acute myocardial infarction (AMI), stroke, or peripheral vascular disease. For patients with acute coronary syndrome (ACS) or stable coronary disease, hs-CRP is used to predict future coronary events.
Ranges of hs-CRP in prediction of risk for CVD are:
<1.0 mg/L Low CVD risk
1.0-3.0 mg/L Average risk for CVD
>3.0 mg/L High risk for future CVD
If results are >10.0 mg/L, the patient should be evaluated for an acute inflammatory condition.
Chemistry
A high-sensitivity C-reactive protein (hs-CRP) test result of 5 mg/L (normal = < 1 mg/L) may indicate which of the following?
A) High risk for future CVD
B) Low risk for cardiovascular disease (CVD)
C) Acute inflammatory condition
3. Dce is found in 4% of whites and 44% of blacks.
DCe is found in 42% of whites and 17% of blacks.
DcE is found in 14% of whites and 11% of blacks.
dce is found in 37% of whites and 26% of blacks.
Blood bank
The most common Rh haplotype among whites is:
A) dce
B) Dce
C) DCe
D) DcE
4. Gamma globulin (anti-D) is given to Rh-negative mothers to prevent any D antibody production, which could cause harmful effects in future pregnancies with an Rh-positive fetus. The administered anti-D will bind fetal Rh-positive cells that may come from the fetus in vivo; therefore the mother will not produce anti-D herself, preventing sensitization.
A solution of gamma globulins containing anti-Rh (D) is given to an Rh (D) negative mother to:
A) Neutralize any of the child's antibody that may have passed the placental barrier
B) Prevent fetal cells from initially sensitizing the mother
C) Neutralize any natural maternal antibodies present
D) Prevent greater antibody response in a previously sensitized mother
5. As maturation continues in the granulocytic series the nucleus of the metamyelocyte becomes kidney or bean shaped.
Identify the cell in this illustration indicated by the arrow:
A) Myeloblast
B) Monocyte
C) Metamyelocyte
D) Promonocyte
Solutions:
| Question # 1 Answer: E | Question # 2 Answer: A | Question # 3 Answer: C | Question # 4 Answer: B | Question # 5 Answer: C |
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